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http://www.revoptom.com/content/c/20600/
VOLUME 1, NUMBER 52
MAY 2, 2011

WHEN IT COMES TO EXAMINING A POTENTIALLY MALIGNANT MELANOMA, BE SURE TO USE THE ABCDE RULE.
One of the best pearls for determining whether a nevus on the skin (or the ocular surface) might be malignant is to apply the ABCDE rule:
  • Courtesy National Cancer Institute Click here to view larger image.
    Asymmetry–One half of the lesion appears different from the other half.
  • Border–The border is irregular or notched, rather than even.
  • Color–The color is varied with shades of black, brown or tan.
  • Diameter–The diameter is greater than 6mm (or the size of a pencil eraser)
  • Evolving–You note any progressive change, including pain or tenderness, bleeding, redness or swelling, or the development of a new bump or nodule.
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