References
1. Tripathi, R. C. (1977a). "Uveoscleral drainage of aqueous humour." Exp Eye Res . 25 (suppl): 305-308.
2. Gabelt, B. & Kaufman, P. (1989). "Prostaglandin F increases uveoscleral outflow inthe cynomolgus monkey." Exp Eye Res 49: 389-402.
3. Bárány, E. (1963). "A mathematical formulation of intraocular pressure as dependent on secretion, ultrafiltration, bulk outflow, and osmotic readsorption of fluid." Invest Ophthalmol 2: 584-590.
4. Gong, H., Tripathi, R. C., & Tripathi, B. J. (1996). "Morphology of the aqueous outflow pathway." Microscop Res Tech 33: 336-367.
5. Bárány, E. H. (1956). "The action of different kinds of hyaluronidase on the resistance to flow through the anterior chamber." Acta Ophthalmol 34: 397-403.
6. McEwen, W. K. (1958). "Application of Poiseuille's law to aqueous outflow." Arch Ophthamol 60: 290.
7. Knepper, P. A., Goossens, W., Hvizd, M., Palmberg, P. F. (1996a) "Glycosaminoglycans of the human trabecular meshwork in primary open-angle glaucoma." Invest Ophthalmol Vis Sci. 37:1360-1367.
8. Gong, H., Underhill, C.B. and Freddo, T. F. (1994). "Hyaluronan in the bovine ocular anterior segment, with emphasis on the outflow pathways." Invest. Ophthalmol.Vis. Sci. 35: 4328-4332.
9. Hubbard, W. C., Johnson, M., Gong, H., Gabelt, B. T., Peterson, J. A., Sawhney, R., Freddo, T. and Kaufman P.L. (1997). "Intraocular pressure and outflow facility are unchanged following acute and chronic intracameral chondroitinase ABC and hyaluronidase in monkeys." Exp Eye Res 65:177-90.
10. Kamm, R. D., Palaszewski, B. A. & Johnson, M. C. (1983). "Calculation of flow resistance in the juxtacanalicular meshwork. ARVO Abstracts." Invest Ophthalmol Vis Sci 24: 135.
11. Seiler, T. & Wollensak, J. (1985). "The resistance of the trabecular meshwork to aqueous humor outflow." Albrecht von Graefe's Arch Clin Exp Ophthalmol 223: 88-91.
12. Ethier, C. R., Kamm, R. D., Palaszewski, B. A., Johnson, M. C., & Richardson, T. M. (1986). "Calculations of flow resistance in the juxtacanalicular meshwork." Invest Ophthalmol Vis Sci 27: 1741-1750.
13. Mäepea, O. & Bill, A. (1992). "Pressures in the juxtacanalicular tissue and Schlemm's canal in monkeys." Exp Eye Res 54: 879-883.
14. Johnson, M. & Erickson, K. (2000). Mechanisms and routes of aqueous humor drainage. Principles and Practice of Ophthalmology. D. M. Albert and F. A. Jakobiec. Philadelphia, WB Saunders Co. Volume 4: Glaucoma, Chapter 193B: 2577-2595.
15. Johnson, M. (2006). "'What controls aqueous humour outflow resistance?'" Exp Eye Res 82(4): 545-57.
16. Murphy, C. G., Johnson, M., & Alvarado, J. A. (1992). "Juxtacanalicular tissue in pigmentary and primary open angle glaucoma. The hydrodynamic role of pigment and other constituents." Arch Ophthamol 110: 1779-1785.
17. Ten Hulzen, R. D. & Johnson, D. H. (1996). "Effect of fixation pressure on juxtacanalicular tissue and Schlemm's canal." Invest Ophthalmol Vis Sci 37: 114-124.
18. Gong, H., Ruberti, J., Overby, D., Johnson, M., & Freddo, T. F. (2002). "A new view of the human trabecular meshwork using quick-freeze, deep-etch electron microscopy." Exp Eye Res 75: 347-358.
19. Ye, W., Gong, H., Sit, A., Johnson, M., and Freddo, T. F. (1997). "Interendothelial junctions in normal human Schlemm's canal respond to changes in pressure." Invest Ophthalmol Vis Sci 38: 2460-2468.
20. Ramos, R. F., Hoying, J. B., Witte, M. H. & Stamer, W. D. (2007) "Schlemm's canal endothelia, lymphatic or blood vasculature?" J. Glaucoma 16:391-405.
21. Grierson, I. & Lee, W. R. (1977). "Light microscopic quantitation of the endothelial vacuoles in Schlemm's canal." Amer J Ophthalmol 84: 234-246.
22. Grierson, I. & Lee, W. R. (1978). "Pressure effects on flow channels in the lining endothelium of Schlemm's canal." Acta Ophthamologica 56: 935-952.
23. Tripathi, R. C. (1977b). "The functional morphology of the outflow systems of ocular and cerbrospinal fluids." Exp Eye Res 25 (suppl): 65-116.
24. Ethier, C. R., Coloma, F. M., Sit, A. J., & Johnson, M. (1998). "Two pore types in the inner wall endothelium of Schlemm's canal." Invest Ophthalmol Vis Sci 39: 2041-2048.
25. Epstein, D.L., & Rohen, J.W. (1991) "Morphology of the trabecular meshwork and inner-wall endothelium after cationized ferritin perfusion in the monkey eye." Invest Ophthalmol Vis Sci. 32:160-71.
26. Allingham, R. R., de Kater, A. W., Ethier, C. R., Anderson, P. J., Hertzmark, E., & Epstein, D. L. (1992). "The relationship between pore density and outflow facility in human eyes." Invest Ophthalmol Vis Sci 33: 1661-1669.
27. Sit, A. J., Coloma, F. M., Ethier, C. R., & Johnson, M. (1997). "Factors affecting the pores of the inner wall endothelium of Schlemm's canal." Invest Ophthalmol Vis Sci 38: 1517-1525.
28. Johnson, M., Chan, D., Reed, A., Christensen, C., Sit, A., & Ethier, C. (2002). "Glaucomatous eyes have a reduced pore density in the inner wall endothelium of Schlemm's canal." Invest Ophthalmol Vis Sci 43: 2950-2955.
29. Johnson, M., Shapiro, A., Ethier, C. R., Kamm, R. D., 1992. Modulation of outflow resistance by the pores of the inner wall endothelium. Invest Ophthalmol Vis Sci 33, 1670-1675.
30. Dvorak-Theobald, G. (1934). "Schlemm's canal: its anastomoses and anatomic relations." Trans Am Ophthalmol Soc. 32: 574-585.
31. Batmanov, IuE. (1968) "The structure of the drainage system of the human eye." [Russian] Vestnik Oftalmologii. 81:27-31.
32. Rohen, J. W. & Rentsch, F. J. (1968) "Morphology of Schlemm's canal and related vessels in the human eye". [German] Albrecht Von Graefes Archiv Klin Exp Ophthalmol. 176:309-29.
33. Rosenquist, R. C. Jr., Melamed, S., Epstein, D. L. (1988) "Anterior and posterior axial lens displacement and human aqueous outflow facility." Invest Ophthalmol Vis Sci. 29:1159-64.
34. deKater, A. W., Spurr-Michaud, S.J. and Gipson, I.K. ((1990). "Localization of smooth muscle myosin-containing cells in the aqueous outflow pathway". Invest Ophthalmol Vis Sci 31: 347-353.
35. Ellingson BA, Grant WM, (1972) Trabeculectomy and sinusotomy in enucleated human eyes. Invest. Ophthalmol 11:21-28.
36. Lütjen-Drecoll, E., Futa, R., & Rohen, J. W. (1981). "Ultrahistochemical studies on tangential sections of trabecular meshwork in normal and glaucomatous eyes." Invest Ophthalmol Vis Sci 21: 563-573.
37. Alvarado, J. A., Yun, A. J. & Murphy, C. G. (1986). "Juxtacanalicular tissue in primary open angle glaucoma and in nonglaucomatous normals." Arch Ophthalmol 104: 1517-28.
38. Rohen, J. W. (1983). "Why is intraocular pressure elevated in chronic simple glaucoma? Anatomical considerations." Ophthalmol 90: 758-765.
39. Johnstone, M. A. & Grant, W. M. (1973). "Pressure dependent changes in the structures of the aqueous outflow system of human and monkey eyes." Am J Ophthalmol 75: 365.
40. Johnson, M. & Kamm, R. D. (1983). "The role of Schlemm's canal in aqueous outflow from the human eye." Invest Ophthalmol Vis Sci 24: 320-325.
41. Moses, R. A. (1979). "Circumferential flow in Schlemm’s canal." Am J Ophthalmol 88: 585-591.
42. Van Buskirk, E. M. (1982). "Anatomic correlates of changing aqueous outflow facility in excised human eyes." Invest Ophthalmol Vis Sci 22: 625-632.
43. Gong, H, Trinkaus-Randall, V., & Freddo, T. F. (1989). "Ultrastructural immunocytochemical localization of elastin in normal human trabecular meshwork." Curr Eye Res 8: 1071-1082.
44. Davies, S.P., Reddy, H., Caivano, M., and Cohen, P. (2000). Specificity and mechanism of action of some commonly used protein kinase inhibitors. J. Biochem 351:95-105.
45. Ishazaki, T., Uehata, M., Tamocihka, I., Keel, J., Nonomura, K., Mackawa, M., Narumiya, S. (2000). "Pharmacological properties of Y-27632, a specific inhibitor of rho-assocatied kinases." Mol Pharmacol 57: 976-983.
46. Uehata, M., Ishizaki, T., Satoh, H., Ono, T., Kawahura, T., Morishita, T., Tamakawa, H., Yamagami, K., Inui, J., Mackawa, M., Narumiya, S. (1997). "Calcium sensitization of smooth muscle mediated by a rho-associated protein kinase in hypertension." Nature 389 (6554):990-994.
47. Kaibuchi, K., Kuronda, S. and Amano, M. (1999). "Regulation of the cytoskeleton and cell adhesion of the rho family GTPases in mammalian cells." Annu Rev Biochem 68: 459-486.
48. Rosenthal, R., Choritz, L., Schlott, S., Bechrakis, N.E., Jaroszewski, J.,Wiederholt, M.,Thieme, H. (2005). "Effects of ML-7 and Y-27632 on carbachol and endothelin-1 induced contraction of bovine trabecular meshwork." Exp Eye Res 80: 837-845.
49. Rao, P.V., Deng, P.F., Kumar, J., Epstein, D.J. (2001). "Modulation of aqueous humor outflow facility by the rho-kinase-specific inhibitor Y-27632." Invest Ophthalmol Vis Sci 42:1029-1037.
50. Honjo, M., Tanihara, H., Inatani, M., Kido, N., Sawamura, T., Yue, B.J., Narumiya, S., Honda, Y. (2001) "Effects of rho-associated kinase inhibitor Y-27632 on intraocular pressure and outflow facility." Invest Ophthalmol Vis Sci 42: 137-144.
51. Tian, B., Gabelt, T.B., Geiger, B., Kaufman, P.L. (1999). "Combined effects of H-7 and cytochalasin-B on outflow facility in monkey eyes." Exp Eye Res 68: 649-655.
52. Coue, M., Brenner, S. L., Spector, I., Korn, E. D. (1987)." Inhibition of actin polymerization by latrunculin-A". FEBS Lett. 213, 316-318.
53. Lyubimova, A., Bershadsky, A. D., Ben-Ze'ev, A. (1997). "Autoregulation of actin synthesis responds to monomeric actin levels." J Cell Biochem. 65, 469-478.
54. Epstein, D. L., Rowlette, L. L., Roberts, B. C. (1999). "Acto-myosin drug effects and aqueous outflow function." Invest Ophthalmol Vis Sci. 40, 74-81.
55. Peterson, J. A., Tian, B., Bershadsky, A. D., Volberg, T., Gangnon, R. E., Spector, I., Geiger, B., Kaufman, P. L. (1999). "Latrunculin-A increases outflow facility in the monkey." Invest Ophthalmol Vis Sci. 40, 931-941.
56. Spector, I., Shochet, N. R., Blasberger, D., Kashman, Y., (1989). "Latrunculins--novel marine macrolides that disrupt microfilament organization and affect cell growth: I. Comparison with cytochalasin D." Cell Motil Cytoskeleton. 13, 127-144.
57. Spector, I., Shochet, N. R., Kashman, Y., Groweiss, A., (1983). "Latrunculins: novel marine toxins that disrupt microfilament organization in cultured cells." Science. 219, 493-495.
58. Peterson, J. A., Tian, B., McLaren, J. W., Hubbard, W. C., Geiger, B., Kaufman, P. L. (2000)."Latrunculins' effects on intraocular pressure, aqueous humor flow, and corneal endothelium". Invest Ophthalmol Vis Sci. 41, 1749-1758.
59. Overby D, Gong H, Qiu, G., Freddo, T.F., Johnson, M. (2002). "The mechanism of increasing outflow facility during washout in the bovine eye." Invest Ophthalmol Vis Sci 43: 3455-3464.
60. Johnson, M., Chen, A., Epstein, D. L., Kamm, R. D. (1991). "The pressure and volume dependence of the rate of wash-out in the bovine eye." Curr Eye Res. 10, 373-375.
61. Sabanay, I., Tian, B., Gabelt, T.B., Geiger, B., Kaufman, P.L. (2004). "Functional and structural reversibility of H-7 effects on the conventional aqueous outflow pathway in monkeys". Exp Eye Res 78:137-150.
62. Sabanay, I., Tian, B., Gabelt, T.B., Geiger, B., Kaufman, P.L. (2006). "Latrunculin-B effects on trabecular meshwork and corneal endothelial morphology in monkeys." Exp Eye Res 82: 236-246.
63. Scott, P. A., Overby, D.R., Freddo, T.F., Gong, H. (2007). "Comparative studies between species that do and do not exhibit the washout effect." Exp Eye Res 84:435-443.
64. Gong, H., Freddo, T.F., and Zhang, Y. (2007) "New morphological findings in primary open angle glaucoma." Invest. Ophthalmol. Vis. Sci. 48: E-Abstract 2079.
65. Battista, S.A., Lu Z., Hofmann, S., Freddo, T.F., Overby, D.R., Gong, H. (2008) "Acute IOP elevation reduces the available area for aqueous humor outflow and induces meshwork herniations into collector channels of bovine eyes". Invest. Ophthalmol. Vis. Sci., 49:5346-52.